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Apis Mellifica therapeutic range of actions as per Boericke Materia Medica
The very characteristic effects of the sting of the bee furnish unerring indications for its employment in disease. Swelling or puffing up of various parts, oedema, red rosy hue, stinging pains, soreness, intolerance of heat, and slightest touch, and afternoon aggravation are some of the general guiding symptoms. Erysipelatous inflammations, dropsical effusions and anasarca, acute, inflammation of kidneys, and other perenchymatous tissues are characteristic pathological states corresponding to Apis. Apis acts especially on outer parts, skin, coatings of inner organs, serous membranes. It produces serous inflammation with effusion, membranes of brain, heart, pleuritic effusion, etc. Extreme sensitiveness to touch and general soreness is marked. Constricted sensations. Sensation of stiffness and as of something torn off in the interior of the body. Much prostration.
Dose.-Tincture to thirtieth potency. In oedematous conditions the lower potencies. Sometimes action is slow; so several days elapse before it is seen to act, and then urine is increased. Apium virus, sixth trituration.
Please note that the dosage of single homoeopathic medicines varies from drug to drug depending upon the condition, age, sensitivity and other things. In some cases they are given as regular doses as 3-5 drops 2-3 times a day whereas in other cases they are given only once in a week, month or even in a longer period.